
Looking for an honest Seed Probiotic review?
As a pharmacist who’s tested Seed’s DS-01 Daily Synbiotic, I wanted to cut through the hype to see if it really delivers on its claims.
Seed is one of the most talked‑about probiotics online — featured on podcasts like Huberman Lab and praised by health experts for its next‑level formulation. But does it live up to the hype (and the premium price)?
Here’s my honest review, covering the science, results, and key things to consider — plus an exclusive 20% discount with code "THEBIRCHERBAR" when you order through our link. Just click on the button above!

What is Seed Probiotic (DS-01 Daily Synbiotic)?
Seed DS-01 is a 2-in-1 probiotic + prebiotic supplement designed to support gut health and beyond. Its outer prebiotic capsule (pomegranate) feeds the inner probiotic strains, ensuring survival through digestion and targeted delivery to the colon — where probiotics do their work.
Unlike typical probiotics, Seed is science-driven, vegan, allergen-free and offers a subscription model to help you save.
Why I Wanted to Review Seed
I review many supplements professionally and personally. Most probiotics are “copy‑paste” formulas with vague claims — but Seed caught my eye for two reasons:
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Diverse scientific depth – 22+ experts (microbiologists, immunologists, gastroenterologists) developed it with strain‑specific clinical data.
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Sustainability focus – refillable glass jar, biodegradable algae foam shipping, and even projects for honeybees and coral reef restoration.
I wanted to test whether this high‑end, eco‑conscious probiotic actually delivers.
My 90‑Day Experience with Seed DS‑01
Noticeable Benefits
- Digestive ease: I don’t suffer major gut issues, but I noticed less bloating after heavy meals and generally felt more “settled.”
- Regularity: My digestion felt more predictable day‑to‑day, even when my diet wasn’t perfect.
- No bad taste / easy to take: Compared to powders or tinctures, swallowing a capsule daily was simple.
The Science (Why It’s Different)
- 24 clinically studied strains: Each chosen for specific benefits (gut barrier, immune, skin, metabolic health).
- 2‑in‑1 capsule design: Ensures survival through stomach acid — many probiotics don’t make it that far.
- Research pedigree: Developed with leading academics across microbiology, immunology, and gastroenterology fields.
What I Didn’t Love
- Price: Around $1.65 USD/day. Worth it for premium quality, but a budget consideration.
- Subscription model: Monthly refill system (cancel anytime) — convenient, but not everyone likes auto‑billing.

Seed Probiotic Benefits (Science + Personal Take)
This breakthrough formulation is paired with innovations in probiotic stabilization and a precision-release system to deliver strains to the colon where the probiotics and colonise and get to work to deliver:
Digestive Health: Reduced bloating and improved gut comfort within weeks.
Immune + Skin Support: Strains studied for gut‑skin axis and immune modulation.
Brain & Mood: Some strains linked to the gut‑brain axis, supporting focus and calm.
(If you want full strain details, Seed’s site is transparent about each strain’s clinical backing — a rare plus in this space.)
Feel free to explore more of the science behind Seed DS-01™ here.
How Seed Compares to Other Probiotics
Feature | Seed DS‑01 | Standard Probiotic |
---|---|---|
Strains | 24 broad-spectrum | 1–10 strains |
Delivery | 2-in-1 prebiotic + probiotic capsule | Standard capsule |
Survival | Survives stomach acid | Many strains destroyed |
Focus | Gut + skin + immune + brain | Mainly gut |
Price | Premium (~$1.67 USD/day) | Cheaper but less comprehensive |
Pros & Cons
Pros
- 24 clinically studied strains with strain‑specific research
- 53.6 Billion AFU
- Supports gut, skin, immunity, and brain health
- Refillable + eco‑friendly packaging
- Simple daily capsule (no taste issues) no refrigeration needed
Cons
- Premium cost compared to standard probiotics
- Subscription model (may not suit everyone)
- Mild digestive changes possible first 1–2 weeks
Side Effects & Who Should Avoid It
Most people tolerate Seed well, I didn't experience any of these when taking this product. However, mild bloating or gas in the first week is common and has been reported (a sign your gut is adjusting).
If you have certain medical conditions, pregnant, or on specific meds, check with your doctor first as other considerations need to be factored in before commencing a probiotic.

Are There Any Seed Probiotic Side Effects?
In the first few days of taking DS-01™, some people experience some gastrointestinal discomfort, abdominal tightness, mild nausea, or changes in their stool.
This is very normal as the body adjusts and can be a sign that the probiotics are viable and attuning to each individual’s unique ecosystem. This is common with most probiotics, however, and not so specific to Seed.
The DS-01™ is also generally safe to take for most people with pre-existing digestive concerns, like IBS, or other health conditions.
However, with all of that being said, we always recommend that you consult your doctor or physician before taking any new supplements of any kind. The individual human body can react differently to any new dietary additions with many factors playing a part from person to person - so it's always safest to check with a medical professional first.

Where To Buy Seed probiotics?
You can buy the DS-01™Daily Synbiotic directly from their website. When you use our discount code "THEBIRCHERBAR" you will save 20% and support us to continue the work we do.
When To Take Seed Probiotics?
It's best to take the DS-01 capsules first thing in the morning on an empty stomach to limit the capsule's exposure to digestive enzymes that can break it down.
Being in capsule form makes it very easy to take on a daily basis - just leave it somewhere where you'll remember to take it.
Seed suggests taking one capsule daily for the first 3 days to give your body a chance to adjust and adapt and then taking 2 capsules daily from day 4 onwards.

FAQs
Is Seed probiotic Worth it?
In my opinion, yes, it is worth the money. I believe it's the best probiotic + prebiotic (synbiotic) available backed by some of the best trials and research ever completed in the probiotic space.
Being 'worth it' to you is completely dependent on your unique health goals and financial circumstances though - so you will have to make the final decision on this!
Are Seed Probiotics FDA Approved?
Dietary Supplements are not reviewed or approved by FDA for safety/efficacy.
However, the FDA does regulate and enforce both dietary supplements (the finished products) and dietary ingredients. Our DS-01™ adheres to all FDA-established protocols for dietary supplements (current Good Manufacturing Practices, or “cGMP”) and also exceeds US regulations for ingredient and product testing and meets the highest global regulatory standards in Europe (EFSA) and Japan (FOSHU).
Does Seed Probiotic Need to be Refrigerated?
No. This is the added benefit that this probiotic is shelf stable and does not need to be kept in the fridge which makes it super convenient to take when travelling or leave at work so you remember to take it.
What If I Don't Like It?
Seed offers a 30-day risk-free 'no questions asked' guarantee!
Get in touch with them within your first month to get a full refund, minus shipping costs.
Where Are Seed Probiotics Made?
Seed is an American company headquartered in Los Angeles, however, the Seed DS-01 Synbiotic is bio-fermented in Europe. There is no Seed probiotics Australia retailer, however, it's incredibly quick and easy to order them direct from the Seed website.

My Verdict
There you have it, the most comprehensive Seed probiotic review on the internet (in our humble opinion!)! And as you've just read - it's a glowing review from us for Seed’s Daily DS-01 Synbiotic.
High-quality prebiotics and probiotics are crucial for maintaining not only great gut health, but also systemic health. More and more studies are discovering the links between maintaining a good gut microbiome by nurturing good bacteria and countless other areas of health within the human body.
With more research, testing and refinements than any other supplements I've ever reviewed (not just probiotics), the Seed Synbiotic will likely have a place in my daily routine for a long time to come.