Metagenics PainX PEA Advanced Capsules
Metagenics PainX PEA Advanced Capsules
Metagenics In Stock

Metagenics PainX PEA Advanced 42 Capsules

PEA support for nerve and inflammatory response

Key Benefits

Helps relieve mild nerve pain and discomfort

Supports nerve health and nervous system function

Contains easily absorbed PEA with saffron for added support

$76.95

Join our Community and receive 10% OFF your first purchase
$76.95

Always read the label and follow the directions for use. Read the warnings before purchase.

What is Metagenics PainX PEA Advanced?

PainX PEA Advanced is a practitioner-formulated supplement designed to provide analgesic and anti-inflammatory support for mild pain, including mild nerve pain, headaches, and migraine-associated discomfort, in healthy individuals.

This advanced formula supports the body’s natural pain-modulating pathways and nervous system function. Palmitoylethanolamide (PEA) plays a role in regulating inflammatory responses and supporting nerve comfort, while thiamine (vitamin B1) contributes to normal nerve function and energy metabolism. Saffron is included to support nervous system balance and emotional wellbeing, helping address contributing factors involved in the pain cycle. Together, these ingredients support a healthy nervous system response and assist with the management of mild pain.

PainX PEA Advanced features Levagen+™ PEA, a clinically studied, highly absorbable form of PEA designed to offer improved bioavailability compared to standard PEA. This allows efficient utilisation while remaining well tolerated for ongoing use.

Encapsulated in vegetarian capsules, PainX PEA Advanced provides a non-habit forming, natural option suitable for daily use as part of a balanced lifestyle to support pain relief, nerve health, and overall wellbeing.

Each capsule contains:

Palmitoylethanolamide (PEA) – as Levagen+™ – A naturally occurring fatty acid amide involved in the regulation of inflammatory and nerve-related responses. PEA supports the body’s endogenous pain-modulating systems and helps maintain nerve comfort by supporting healthy neuroinflammatory balance. The Levagen+™ form is clinically studied for enhanced absorption and bioavailability compared to standard PEA.

Saffron (Crocus sativus, affron®) – A standardised saffron extract traditionally used to support nervous system balance and emotional wellbeing. Saffron helps modulate neurotransmitter activity and supports mood and stress responses, which may contribute to improved pain perception and nervous system resilience.

Vitamin B1 (Thiamine) – An essential vitamin that supports normal nerve conduction, energy metabolism, and nervous system function. Adequate thiamine intake is important for maintaining nerve health and supporting the body’s response to nerve-related discomfort.

Together, these ingredients form a synergistic nerve-support complex that helps support inflammatory balance, nervous system health, and the management of mild pain as part of a holistic approach to wellbeing.

Free from: Animal products, Dairy protein, Lactose, Eggs, Gluten, Wheat, Nuts, Yeast, Soy protein.

Excipients: Citric acid, Colloidal anhydrous silica, Colour, Dl-alpha-tocopheryl acetate, Flavour, Lecithin, Lime oil cold pressed,Malic acid, Maltodextrin, Medium chain triglycerides, Olive oil, PEG-35 castor oil, Silicon dioxide, Stevia rebaudiana.

Adults: Take 1 capsule twice daily, or as directed by your healthcare professional.

This medicine is not to be used for more than 21 consecutive days, and may interact with other prescription analgesic medicines. Please consult your healthcare practitioner before use.

Suitable for individuals 18 years and over. Vitamins supplements should not replace a balanced diet.

If symptoms persist consult your healthcare professional.

“Palmitoylethanolamide (PEA) is a naturally occurring lipid compound produced by the body that plays a role in regulating inflammation and nerve signalling. Supplementing with a clinically studied form such as Levagen+™ PEA helps support the body’s own pain-modulating pathways by addressing neuroinflammatory processes that can contribute to mild nerve pain and discomfort. Because PEA works by supporting underlying regulatory mechanisms rather than masking symptoms, it is considered a well-tolerated option for ongoing nerve and pain support as part of a balanced approach to wellbeing.”

— Isabella Truong, Pharmacist

Standard Shipping - $12.95

  • 2 – 7 business days metro
  • 7 – 14 business days regional/remote

Express Shipping - $16.95

  • 1 – 3 business days metro
  • 3 – 7 business days regional/remote

Orders over $199 (after discounts) - Free*

  • 2 – 14 business days *(Standard shipping)

We aim to process all orders within 2–3 business days of your order being placed.

Orders placed on weekends or NSW public holidays will be processed on the next business day.

Delivery timeframes begin once your order has been dispatched. Actual times may vary due to courier network delays or regional location.

For more detailed information, see our Shipping & Delivery Policy.

Frequently asked question

PEA (Palmitoylethanolamide) is a naturally occurring fatty acid compound that your body produces to help regulate pain and inflammatory responses. It works by supporting your endocannabinoid system and helps calm overactive nerve signals. PEA is particularly beneficial for nerve-related discomfort and has been researched for various pain conditions.

Levagen+™ is the 'gold standard' preparation of PEA, designed to target nerve pain and inflammation effectively. It mimics the body’s own endogenous PEA but utilizes LipiSperse® delivery technology to bypass the absorption issues common with standard PEA. This ensures consistent therapeutic levels in the body to help break the pain cycle and support nervous system function.

No, PainX PEA Advanced is suitable for daily ongoing support. It is mean for short term use for mild pain ailments like headaches or mild nerve pain, for a maximum of 21 consecutive days of use. If your symptoms persists then you should consult your healthcare professional.

PainX PEA Advanced does not typically cause drowsiness, making it suitable for daytime use. Palmitoylethanolamide (PEA) works through the endocannabinoid system rather than sedative pathways, so it won't affect alertness or concentration.

Regarding medication interactions, PEA itself has a favourable safety profile with no established significant drug interactions. However, this formula contains saffron, which may interact with certain medications including antidepressants, blood thinners, and blood pressure medications.

If you're taking any prescription medications — particularly for mood, pain, or cardiovascular conditions — consult your healthcare practitioner before use to ensure this product is appropriate for you.